Integron associated mobile genes
نویسندگان
چکیده
منابع مشابه
Integron associated mobile genes
Lateral gene transfer (LGT) impacts on the evolution of prokaryotes in both the short and long-term. The short-term impacts of mobilized genes are a concern to humans since LGT explains the global rise of multi drug resistant pathogens seen in the past 70 years. However, LGT has been a feature of prokaryotes from the earliest days of their existence and the concept of a bifurcating tree of life...
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Deletion of individual antibiotic resistance genes found within the variable region of integrons is demonstrated. Evidence for gene duplications and rearrangements resulting from the insertion of gene units at new locations is also presented. Deletion, duplication, and rearrangement occur only in the presence of the integron-encoded DNA integrase. These events are precise and involve loss or ga...
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Clinically important antibiotic resistance genes were detected in culturable bacteria and class 1 integron gene cassettes recovered from suspended floc, a significant aquatic repository for microorganisms and trace elements, across freshwater systems variably impacted by anthropogenic activities. Antibiotic resistance gene cassettes in floc total community DNA differed appreciably in number and...
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In a recent publication in Cell (Jia et al., 2013), the authors conclude from bioinformatics, genetic, and biochemical analyses that a conserved sequence element associated with antibiotic resistance genes represents a novel widespread riboswitch class for certain aminoglycosides. Below, we point out previously reported functions for this element that were not discussed by the authors, and we n...
متن کاملCorrelation of quinolone-resistance, qnr genes and integron carriage in multidrug-resistant community isolates of Klebsiella spp.
Objective(s): Plasmid-mediated quinolone resistance (PMQR) determinants and integrons have a considerable contribution to bacterial drug resistance in Gram-negative pathogens. We studied the prevalence of PMQR genes and integron carriage in multidrug-resistant community isolates of Klebsiella spp.Materials and Methods: Two hundred and fi...
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ژورنال
عنوان ژورنال: Mobile Genetic Elements
سال: 2012
ISSN: 2159-256X
DOI: 10.4161/mge.19510